Introduction: Carney COMPLEX is an autosomal dominant syndrome that is defined with different tumors including myxoma in different organs, endocrine tumors and lentiginosis lesions. This is the first case report of this syndrome from Iran.Case: The patient is a 27 year old girl, referred with flank pain. Physical examination revealed hirsutism, truncal obesity, hyperpigmantasion and hypertension; Cushing's syndrome was suggested and confirmed with related classic biochemical tests. She had history of cardiac myxoma during her childhood and had been operated twice.Pituitary microadenoma and right adrenal adenoma were reported on MRI and CT-scan, respectively. Initially laparascopic right adrenalectomy was done; as expected, no remission in signs of Cushing's syndrome was observed after surgery. By laparoscopic adrenalectomy of the other site, Cushing's syndrome resolved. Pathologic report of 1st operation was adrenal adenoma with surrounding pigmented micronodular hyperplasia and of the 2nd one was just pigmented micronodular hyperplasia.Conclusion: We have reported a patient with Carney syndrome along with Cushing's syndrome due to bilateral adrenal hyperplasia and an adenoma in contralateral adrenal and microadenoma of the pituitary as an incidentaloma. This is a new presentation of Carney syndrome.

Introduction: Men with unexplained infertility and azoospermia are often observed in the context of genetic defects. The expression of a wide variety of genes is developmentally regulated  during human meiosis. Synaptonemal Protein 3 (SYCP3) gene, located on chromosome 12, encodes a DNA-binding protein as the structural component of the synaptonemal COMPLEX,which mediates the synopsis or homologous pairing of chromosomes during meiosis. Absence of SYCP3 in mice may lead to male infertility as well as female sub-fertility. SYCP3 expression analysis could be a tool for the prediction of human spermatogenesis progression, especially in infertile men.Materials & Methods: SYCP3 mRNA expression in testicular samples of 110 patients with non-obstructive azoospermia were studied in Avesina Infertility Clinic in Tehran, Iran during 2005 and early 2006. Semi-quantitative nested reverse transcriptase-PCR was employed in order to find the strength of gene expression. Using histopathological scoring for all samples, the expression level of SYCP3 during spermatogenesis was also evaluated.Results: Testicular SYCP3 mRNA expression was observed in 67 patients (60.9%). The expression level correlated with the degree of spermatogenic failure (p<0.0001). While this gene had been expressed in patients with hypo-spermatogenesis and maturation arrest, a lack of expression was seen in those with spermatogonial arrest, Sertoli cell-only syndrome and testicular atrophy.Conclusion: These data indicate that SYCP3 is expressed in the human testis and it is restricted to germ cells. Our findings, in association with those obtained in experimental animals, show that lack of SYCP3 expression may have negative effects on spermatogenesis and male fertility. SYCP3 gene expression may help detect specific spermatogenesis stages in conjunction with histopathological findings.

Two spotted spider mite (Tetranychus urticae COMPLEX) is an important pest of  egg-plant in Iran. In the present study, population of eggs and active stages and amount of losses of the spider mite were determined on upper and lower leaves of nine egg-plant cultivars in Varamin during 2001-2002. The experiment was in a randomized complete block design with three replications. Each plot consisted of four rows and on each row ten egg-plants were cultivated. Spider mite population on all cultivars was checked at weekly samplings, from July to October. Number of mites (eggs and active stages) on upper and lower leaves were then counted by stereo binocular microscope. Loss percent of mite was assessed by measuring the weight of ten randomly selected fruits of each cultivar in three replications at fifteen day intervals during fruiting period. Analysis of variance on data showed significant differences of mite population on upper and lower leaves of different cultivars and also among the cultivars. In 2000, the highest mean populations of active mites on lower leaves, 37.80 and 46.87, and on upper leaves, 27.19 and 38.08 were recorded on Borazjan cv. in naturally and artificially infested treatments, respectively. In 2001, egg and active mite populations on cultivar were significantly different only in artificially infested treatment. The maximum numbers of eggs (63.47) and active stage (107.94) were recorded on Imami 905 cultivar. Maximum and minimum losses of 69.42% and 12.86% were recorded on Imami 905 and Ghalami Varamin cultivars. These cultivars were determined as the most susceptible and resistant cultivars to mite damage, respectively.

In order to determine the fumonisin producing isolates of the Fusarium fujikuroi species COMPLEX (FFSC), associated with infected spikes, and ear rot of grass plants, we examined 78 samples collected from Kermanshah province, Iran. Based on morphological characters, twenty two isolates assigned to the FFSC and were identified as F. proliferatum (ten isolates), F. verticillioides (seven isolates), and F. subglutinans (five isolates). This was additionally approved using the specific primers of F. verticillioides, F. proliferatum, and F. subglutinans, i.e. VER1/VER2, PRO1/PRO2, and SUB1/SUB2, respectively. PCR–based detection of the fumonisin–producing isolates of FFSC was also achieved using the primers FUM1 F/FUM1 R. Out of twenty two isolates, eleven isolates (50%) determined as fumonisin chemotype.

A B S T R A C TThe purpose of this study is to measure the level of sustainability of residential COMPLEXes in Gorgan and to identify the impact of social capital and its dimensions on the concept of housing sustainability. The research method is descriptive and survey type. The statistical population of the research includes all the residential COMPLEXes of Gorgan city, of which 268 cases were determined using Cochran's formula as a statistical sample and were selected and studied using the two-stage cluster sampling method.. A researcher-made questionnaire with an answer package was used to collect data. Its validity was confirmed using the formal method and its reliability using Cronbach's alpha coefficient for the concept of social capital (α = 0.879) and housing sustainability (α = 0.810), respectively. The findings showed that there is a significant positive relationship between social capital and its dimensions with the dependent variable, i.e. housing sustainability variable and its four dimensions. The results showed that the integrated model in the present study was able to explain the relationship between social capital and the concept of housing sustainability to an acceptable extent. Therefore, this model can be useful for other urban areas of the countryExtended AbstractIntroductionThe home is the source and destination of all human life; and man leaves it for work and social activity, and after doing it and gaining experience, he returns home. Therefore, the category of housing is a broad and COMPLEX category that has various dimensions. This concept, in addition to the place in the physical concept, includes all the services and facilities needed by an individual or family that need it to live. To this end, housing planning requires in-depth studies in various social, cultural and historical fields. Today, the mere attention to the economy, many human, social, indigenous and cultural values have been lost in the course of these unprincipled constructions that have grown and are growing at an unprecedented rate. Hence, housing architecture does not simply mean designing or constructing space for human life; For this reason, in housing architecture, especially social housing, apart from the design of human habitation, other dimensions of human life and habitation must also be considered. Based on what has been mentioned, in our country, today most of the economic dimension and consequently a small increase in the construction and architecture of residential COMPLEXes and other dimensions of sustainable development, including social, cultural, physical and The environment is neglected. Lack of adequate housing, as housing that has the least incompatibility with the natural environment around it and in a wider area with the region and the world; it creates problems for the city and its residents. Meanwhile, residential COMPLEXes in Gorgan are no exception to this rule. COMPLEXes that are designed with only the economic dimension in mind, the result of which is the construction of housing in different parts of the city, which has the least coordination and compatibility with other aspects of sustainable development. Given the above, the importance of the present study, attention to the principles of sustainable development and the need to create and expand social capital for human societies, in the space that was drawn is very important. MethodologyAccording to the purpose of the research and the level of data analysis, the survey method has been used to collect data. For this purpose, a researcher-made questionnaire was used to obtain information. The statistical population of the study includes all residential COMPLEXes in Gorgan. The sample size is 268 based on Cochran's logical formula. Two-stage cluster random sampling method is used. So that the statistical population is divided into clusters and homogeneous groups and then the quota of groups or clusters is determined in proportion to the frequency distribution of each cluster. In the next step, residential COMPLEXes are selected as a statistical sample from each cluster. To verify the validity of the tool, the formal validation method (referring to professors and specialists) has been used. Cronbach's alpha method was also used to determine the reliability of the instrument. Results and discussionAccording to the results of t-test, it can be said that the social capital index is not desirable. The average of social capital index is lower than the hypothetical average. This means that the amount of social capital of the residents of residential COMPLEXes in Gorgan is not at the desired level. This is if the level of stability of residential COMPLEXes in Gorgan is at a desirable level. Also, there is a significant relationship between housing sustainability and social capital. And the order of the effect of social capital variable on the dimensions of economic, social, physical and environmental sustainability. Based on the results of the probability ratio of the Chi-square value model is less than 0.01, it can be said that the regression model is a good model in which independent variables are well able to explain the changes of the dependent variable. The results of hierarchical regression analysis showed that the estimated value of the social interaction variable is equal to 1.184, which shows that assuming the effect of all model variables remains constant, an increase in the independent social interaction variable increases by 1.184 units. In logarithmic ratios, the dependent variable (housing stability) will be associated. Prioritization of the effectiveness of the studied factors indicates that the factor of formal participation has the first place in determining the sustainability of housing. After this factor, the mental class factor is in the second place, then the residential home ownership factor is in the third place. ConclusionOne of the issues that has attracted everyone's attention in recent decades is housing and its sustainable development, which is in line with human development. An important point that has been addressed in the documents of the Second Human Settlement Summit is the importance of the role of sustainable housing and the provision of adequate housing for the people in the development process. Various factors such as architectural style, climate, geography and customs are influential in housing design in different places. In the meantime, the role of social factors or in other words social capital cannot be ignored; Because social capital is rooted in the structure and social norms of society and is generally a combination of trust, communication network, social norms and social relations at the individual and community level. Accordingly, the main purpose of this study is to measure the social capital of residents and the sustainability of residential COMPLEXes in Gorgan. Based on the results, the four dimensions of the dependent variable are affected by the social capital variable. This means that the existence of concepts such as trust, interaction, participation, etc. in residential COMPLEXes, can provide the stability of the residential COMPLEX. As long as the residents of a COMPLEX have an effective and reciprocal relationship with each other, the stability of the residential COMPLEX is provided; Residents to protect the COMPLEX facilities, provide security, visual beauty, hygiene and cleanliness, rehabilitate or create space Green and ... will interact and participate with each other.FundingThere is no funding support. Authors’ ContributionAuthors contributed equally to the conceptualization and writing of the article. All of the authors approved the content of the manuscript and agreed on all aspects of the work declaration of competing interest none. Conflict of InterestAuthors declared no conflict of interest. Acknowledgments We are grateful to all the scientific consultants of this paper.